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	<title>Depressed Les&#187; N-acetylcysteine</title>
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	<description>Depressed Trichotillomaniac with Social Anxiety</description>
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		<title>N-acetylcysteine</title>
		<link>http://www.depressedles.com/n-acetylcysteine/</link>
		<comments>http://www.depressedles.com/n-acetylcysteine/#comments</comments>
		<pubDate>Tue, 01 Sep 2009 12:22:35 +0000</pubDate>
		<dc:creator>Leslie</dc:creator>
				<category><![CDATA[OCD]]></category>
		<category><![CDATA[Therapy]]></category>
		<category><![CDATA[Trichotillomania]]></category>
		<category><![CDATA[N-acetylcysteine]]></category>
		<category><![CDATA[NAC]]></category>
		<category><![CDATA[symptoms]]></category>

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		<description><![CDATA[My trichotillomania symptoms had been getting worse since getting a puppy.  My stress levels have been considerably higher and I've been functioning on less sleep. ]]></description>
			<content:encoded><![CDATA[<p><span style="color: #7e609f;">A few weeks ago Tareak came across <a href="http://www.time.com/time/health/article/0,8599,1909704,00.html" target="_self">an article </a>describing a treatment for <a href="http://www.depressedles.com/trichotillomania/" target="_self">Trichotillomania</a>.  Currently there is no cure for Trichotillomania, but there are some different ways it can be managed.</span></p>
<p><span style="color: #7e609f;">This article described a small study done with 50 people.  They used an over-the-counter antioxidant called N-acetylcysteine to assist in the treatment of trichotillomania symptoms.  There was an over 50% success rate in comparison to the 16% success rate in the group receiving the placebo. <em><a href="http://en.wikipedia.org/wiki/N-acetylcysteine" target="_self">N-acetylcysteine (abbreviated NAC), is a pharmaceutical drug used mainly as a Mucolytic agent and in the management of paracetamol (acetaminophen) overdose</a>, </em>but it has shown to be somewhat effective in treating OCD and is undergoing clinical trials.</span></p>
<p><span style="color: #7e609f;"><a href="http://www.time.com/time/health/article/0,8599,1909704,00.html" target="_self">The article</a> <em>&#8220;theorizes that trichotillomania may be a kind of grooming irregularity that falls into the obsessive-compulsive family of disorders. &#8220;Some parrots pull out all their feathers,&#8221; he says. &#8220;Some mice pull out all their fur.&#8221;"</em></span></p>
<p><span style="color: #7e609f;"><em> &#8220;That may explain why the antioxidant N-acetylcysteine can help prevent it. The compound is thought to work by reducing the synaptic release of a neurotransmitter called glutamate. As Grant told me, glutamate is the communication chemical that &#8220;tells the brain, &#8216;Do it! Do it! Do it! Do it!&#8217; And the rest of the brain can be overwhelmed by this drive state.&#8221; Reduce glutamate and you may reduce the drive state. Previous studies have suggested the supplement may also reduce urges to use cocaine and to gamble.&#8221;</em></span></p>
<p><span style="color: #7e609f;">My trichotillomania symptoms had been getting worse since getting a puppy.  My stress levels have been considerably higher and I&#8217;ve been functioning on less sleep.  About 2 weeks ago Tareak and I picked up some NAC and I&#8217;ve been taking it daily.  I probably won&#8217;t notice any difference for another couple months, but hopefully it will help!</span></p>
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